What Are GLP-1 Medications and How Do They Work?
Everything you need to know about semaglutide, tirzepatide, and how GLP-1 receptor agonists help you lose weight.
By Dr. Linda Moleon, MD, MD
What Are GLP-1 Medications?
GLP-1 (glucagon-like peptide-1) receptor agonists are a class of medications originally developed for type 2 diabetes that have shown remarkable results for weight loss.
How They Work
GLP-1 medications mimic a natural hormone your body produces after eating. This hormone:
- Signals fullness to your brain, reducing appetite
- Slows stomach emptying, helping you feel satisfied longer
- Regulates blood sugar, reducing cravings
Types of GLP-1 Medications
Semaglutide (Ozempic/Wegovy class) targets GLP-1 receptors and produces an average of 15% body weight loss.
Tirzepatide (Mounjaro/Zepbound class) targets both GLP-1 AND GIP receptors, producing 20-25% average weight loss — the strongest results in clinical trials.
Is It Right for You?
GLP-1 medications are typically prescribed for adults with a BMI of 27+ (with weight-related conditions) or 30+. Take our quiz to find out which option is right for you.
Based on clinical trial data for the referenced FDA-approved medication. Individual results vary. These results do not establish the safety or effectiveness of compounded medications.