Insurance Products
💊 Semaglutide vs. Tirzepatide Comparison
| Feature | Semaglutide | Tirzepatide |
|---|---|---|
| Brand Names | Wegovy®, Ozempic® (FDA-approved branded prescription medications) | Zepbound®, Mounjaro® (FDA-approved branded prescription medications) |
| Mechanism | GLP-1 receptor agonist (mimics natural hormone that regulates appetite and blood sugar) | Dual GLP + GLP-1 receptor agonist (targets two hormones for stronger effect) |
| Effectiveness | Average 15% body weight reduction over 12–18 months | Average 20–22% body weight reduction over 12–18 months |
| Appetite Control | Strong appetite suppression | More potent appetite suppression and energy balance |
| Onset of Results | Some patients may notice changes within 4–6 weeks; results vary. | Some patients may notice changes within 2–4 weeks; results vary. |
| Dosing Frequency | Weekly injection | Weekly injection |
| Common Side Effects | Nausea, constipation, diarrhea, fatigue | Similar side effects; may be slightly stronger early on |
| Best For | First-time GLP-1 users or those preferring gradual titration | Patients needing faster results or who’ve plateaued on Semaglutide |
Semaglutide
- Brand Names
- Wegovy®, Ozempic® (FDA-approved branded prescription medications)
- Mechanism
- GLP-1 receptor agonist (mimics natural hormone that regulates appetite and blood sugar)
- Effectiveness
- Average 15% body weight reduction over 12–18 months
- Appetite Control
- Strong appetite suppression
- Onset of Results
- Some patients may notice changes within 4–6 weeks; results vary.
- Dosing Frequency
- Weekly injection
- Common Side Effects
- Nausea, constipation, diarrhea, fatigue
- Best For
- First-time GLP-1 users or those preferring gradual titration
Tirzepatide
- Brand Names
- Zepbound®, Mounjaro® (FDA-approved branded prescription medications)
- Mechanism
- Dual GLP + GLP-1 receptor agonist (targets two hormones for stronger effect)
- Effectiveness
- Average 20–22% body weight reduction over 12–18 months
- Appetite Control
- More potent appetite suppression and energy balance
- Onset of Results
- Some patients may notice changes within 2–4 weeks; results vary.
- Dosing Frequency
- Weekly injection
- Common Side Effects
- Similar side effects; may be slightly stronger early on
- Best For
- Patients needing faster results or who’ve plateaued on Semaglutide
Information above is for educational purposes only and is based on published data for FDA-approved branded medications, not compounded products. Compounded medications are not FDA-approved, and individual results vary.



